My husband had extremely high liver enzymes after gettting a routine blood test (7/10/09). When I asked the Dr. about these, she said it wouldn't hurt(she's not real big on natural supplements). He started taking them on 7/30/09 and had another blood test on 8/31/09 and his enzymes dropped about 24%. I was wishing for a lower number but the numbers weren't weren't bad for the first 30-60 days. He is going to keep taking them and hoping his numbers keep declining.
I have been using Milk Thistle for a while now and have found that it has really helped my liver. I have been put on steroids for the rest of my life and my recent liver ultrasound scan was extremely improved.